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Cortical sinus probing, S1P(1)-dependent entry and flow-based capture of egressing T cells
The cellular dynamics of lymphocyte egress from lymph nodes are poorly defined. Here, we visualized the branched organization of lymph node cortical sinuses and found that after entry some T cells were retained while others returned to the parenchyma. Sphingosine-1-phosphate receptor 1 (S1P(1))-defi...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2710451/ https://www.ncbi.nlm.nih.gov/pubmed/19060900 http://dx.doi.org/10.1038/ni.1682 |