RNA interference targeting the platelet-derived growth factor receptor β subunit ameliorates experimental hepatic fibrosis in rats

BACKGROUND/AIMS: Platelet-derived growth factor (PDGF) is the strongest stimulator of the proliferation of hepatic stellate cells (HSCs). PDGF receptor β subunit (PDGFR-β) is acquired on HSCs proliferation induced by PDGF. In this study, we aim to investigate the effect of PDGFR-β small interference...

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Detalles Bibliográficos
Autores principales: Chen, Si-Wen, Zhang, Xing-Rong, Wang, Chong-Ze, Chen, Wei-Zhong, Xie, Wei-Fen, Chen, Yue-Xiang
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2008
Materias:
Basic Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2710794/
https://www.ncbi.nlm.nih.gov/pubmed/18466260
http://dx.doi.org/10.1111/j.1478-3231.2008.01759.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2710794/
https://www.ncbi.nlm.nih.gov/pubmed/18466260
http://dx.doi.org/10.1111/j.1478-3231.2008.01759.x

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