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RNA interference targeting the platelet-derived growth factor receptor β subunit ameliorates experimental hepatic fibrosis in rats

BACKGROUND/AIMS: Platelet-derived growth factor (PDGF) is the strongest stimulator of the proliferation of hepatic stellate cells (HSCs). PDGF receptor β subunit (PDGFR-β) is acquired on HSCs proliferation induced by PDGF. In this study, we aim to investigate the effect of PDGFR-β small interference...

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Detalles Bibliográficos
Autores principales:	Chen, Si-Wen, Zhang, Xing-Rong, Wang, Chong-Ze, Chen, Wei-Zhong, Xie, Wei-Fen, Chen, Yue-Xiang
Formato:	Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2008
Materias:	Basic Studies
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2710794/ https://www.ncbi.nlm.nih.gov/pubmed/18466260 http://dx.doi.org/10.1111/j.1478-3231.2008.01759.x

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