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Gsα signalling suppresses PPARγ2 generation and inhibits 3T3L1 adipogenesis

Since TSH receptor (TSHR) expression increases during adipogenesis and signals via cAMP/phospho-cAMP-response element binding protein (CREB), reported to be necessary and sufficient for adipogenesis, we hypothesised that TSHR activation would induce preadipocyte differentiation. Retroviral vectors i...

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Detalles Bibliográficos
Autores principales: Zhang, Lei, Paddon, Carol, Lewis, Mark D, Grennan-Jones, Fiona, Ludgate, Marian
Formato: Texto
Lenguaje:English
Publicado: BioScientifica 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2710974/
https://www.ncbi.nlm.nih.gov/pubmed/19460852
http://dx.doi.org/10.1677/JOE-09-0099