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Immunization with thyroglobulin induces Graves'-like disease in mice
We immunized AKR/N mice with bovine thyroglobulin (Tg) once every 2 weeks and monitored their time-dependent changes in (125)I uptake activity in the thyroid glands. After 3 months, anti-Tg antibody was positive in all sera from the immunized mice. Serum free tri-iodothyronine (T(3)) and free thyrox...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioScientifica
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2710975/ https://www.ncbi.nlm.nih.gov/pubmed/19491147 http://dx.doi.org/10.1677/JOE-09-0089 |