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Evidence for a mitochondrial localization of the retinoblastoma protein
BACKGROUND: The retinoblastoma protein (Rb) plays a central role in the regulation of cell cycle, differentiation and apoptosis. In cancer cells, ablation of Rb function or its pathway is a consequence of genetic inactivation, viral oncoprotein binding or deregulated hyperphosphorylation. Some recen...
Autores principales: | , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2711044/ https://www.ncbi.nlm.nih.gov/pubmed/19555499 http://dx.doi.org/10.1186/1471-2121-10-50 |