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Effect of hydroxyurea on the promoter occupancy profiles of tumor suppressor p53 and p73
BACKGROUND: The p53 tumor suppressor and its related protein, p73, share a homologous DNA binding domain, and mouse genetics studies have suggested that they have overlapping as well as distinct biological functions. Both p53 and p73 are activated by genotoxic stress to regulate an array of cellular...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2711048/ https://www.ncbi.nlm.nih.gov/pubmed/19558638 http://dx.doi.org/10.1186/1741-7007-7-35 |