PUMA and Bax-induced Autophagy Contributes to Apoptosis

The p53-inducible BH3-only protein PUMA is a key mediator of p53-dependent apoptosis, and PUMA has been shown to function by activating Bax and mitochondrial outer membrane permeabilization. In this study we describe an ability of PUMA to induce autophagy that leads to the selective removal of mitoc...

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Detalles Bibliográficos
Autores principales: Yee, Karen S., Wilkinson, Simon, James, John, Ryan, Kevin M., Vousden, Karen H.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2711052/
https://www.ncbi.nlm.nih.gov/pubmed/19300452
http://dx.doi.org/10.1038/cdd.2009.28

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2711052/
https://www.ncbi.nlm.nih.gov/pubmed/19300452
http://dx.doi.org/10.1038/cdd.2009.28

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