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Drosophila HtrA2 is dispensable for apoptosis but acts downstream of PINK1 independently from Parkin
High Temperature Requirement A2 (HtrA2/Omi) is a mitochondrial protease that exhibits pro-apoptotic and cell protective properties and has been linked to Parkinson disease (PD). Impaired mitochondrial function is a common trait in PD patients, and is likely to play a significant role in pathogenesis...
Autores principales: | , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2711053/ https://www.ncbi.nlm.nih.gov/pubmed/19282869 http://dx.doi.org/10.1038/cdd.2009.23 |