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Drosophila HtrA2 is dispensable for apoptosis but acts downstream of PINK1 independently from Parkin

High Temperature Requirement A2 (HtrA2/Omi) is a mitochondrial protease that exhibits pro-apoptotic and cell protective properties and has been linked to Parkinson disease (PD). Impaired mitochondrial function is a common trait in PD patients, and is likely to play a significant role in pathogenesis...

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Detalles Bibliográficos
Autores principales:	Tain, Luke S., Chowdhury, Ruhena B., Tao, Ran N., Plun-Favreau, Helene, Moisoi, Nicoleta, Martins, L. Miguel, Downward, Julian, Whitworth, Alexander J., Tapon, Nicolas
Formato:	Texto
Lenguaje:	English
Publicado:	2009
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2711053/ https://www.ncbi.nlm.nih.gov/pubmed/19282869 http://dx.doi.org/10.1038/cdd.2009.23

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