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Regulation of TORC1 by Rag GTPases in nutrient response

TORC1 (Target of rapamycin complex 1) has a critical role in the regulation of cell growth and cell size. A wide range of signals, including amino acids, is known to activate TORC1. Here, we report the identification of Rag GTPases as novel activators of TORC1 in response to amino acid signals. Knoc...

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Detalles Bibliográficos
Autores principales: Kim, Eunjung, Goraksha-Hicks, Pankuri, Li, Li, Neufeld, Thomas P., Guan, Kun-Liang
Formato: Texto
Lenguaje:English
Publicado: 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2711503/
https://www.ncbi.nlm.nih.gov/pubmed/18604198
http://dx.doi.org/10.1038/ncb1753