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Segregation of sphingolipids and sterols during formation of secretory vesicles at the trans-Golgi network

The trans-Golgi network (TGN) is the major sorting station in the secretory pathway of all eukaryotic cells. How the TGN sorts proteins and lipids to generate the enrichment of sphingolipids and sterols at the plasma membrane is poorly understood. To address this fundamental question in membrane tra...

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Detalles Bibliográficos
Autores principales: Klemm, Robin W., Ejsing, Christer S., Surma, Michal A., Kaiser, Hermann-Josef, Gerl, Mathias J., Sampaio, Julio L., de Robillard, Quentin, Ferguson, Charles, Proszynski, Tomasz J., Shevchenko, Andrej, Simons, Kai
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2711577/
https://www.ncbi.nlm.nih.gov/pubmed/19433450
http://dx.doi.org/10.1083/jcb.200901145