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GNL3L stabilizes the TRF1 complex and promotes mitotic transition

Telomeric repeat binding factor 1 (TRF1) is a component of the multiprotein complex “shelterin,” which organizes the telomere into a high-order structure. TRF1 knockout embryos suffer from severe growth defects without apparent telomere dysfunction, suggesting an obligatory role for TRF1 in cell cyc...

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Detalles Bibliográficos
Autores principales: Zhu, Qubo, Meng, Lingjun, Hsu, Joseph K., Lin, Tao, Teishima, Jun, Tsai, Robert Y.L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2711588/
https://www.ncbi.nlm.nih.gov/pubmed/19487455
http://dx.doi.org/10.1083/jcb.200812121