Bub1 regulates chromosome segregation in a kinetochore-independent manner

The kinetochore-bound protein kinase Bub1 performs two crucial functions during mitosis: it is essential for spindle checkpoint signaling and for correct chromosome alignment. Interestingly, Bub1 mutations are found in cancer tissues and cancer cell lines. Using an isogenic RNA interference compleme...

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Detalles Bibliográficos
Autores principales: Klebig, Christiane, Korinth, Dirk, Meraldi, Patrick
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2711590/
https://www.ncbi.nlm.nih.gov/pubmed/19487456
http://dx.doi.org/10.1083/jcb.200902128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2711590/
https://www.ncbi.nlm.nih.gov/pubmed/19487456
http://dx.doi.org/10.1083/jcb.200902128

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