Molecular Mimicry of SUMO Promotes DNA Repair

Rad60 family members contain functionally enigmatic, integral SUMO-like domains (SLDs). Intriguingly, we find that despite their divergence from SUMO, each Rad60 SLD interacts with a subset of SUMO pathway enzymes. SLD2 specifically binds the SUMO E2 conjugating enzyme (Ubc9), whereas SLD1 binds the...

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Detalles Bibliográficos
Autores principales: Prudden, J., Perry, J.J.P., Arvai, A., Tainer, J.A., Boddy, M.N.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2711901/
https://www.ncbi.nlm.nih.gov/pubmed/19363481
http://dx.doi.org/10.1038/nsmb.1582

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2711901/
https://www.ncbi.nlm.nih.gov/pubmed/19363481
http://dx.doi.org/10.1038/nsmb.1582

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