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Conserved cryptic recombination signals in Vκ gene segments are cleaved in small pre-B cells
BACKGROUND: The cleavage of recombination signals (RS) at the boundaries of immunoglobulin V, D, and J gene segments initiates the somatic generation of the antigen receptor genes expressed by B lymphocytes. RS contain a conserved heptamer and nonamer motif separated by non-conserved spacers of 12 o...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2711918/ https://www.ncbi.nlm.nih.gov/pubmed/19555491 http://dx.doi.org/10.1186/1471-2172-10-37 |