Epistatic interactions modulate the evolution of mammalian mitochondrial respiratory complex components
BACKGROUND: The deleterious effect of a mutation can be reverted by a second-site interacting residue. This is an epistatic compensatory process explaining why mutations that are deleterious in some species are tolerated in phylogenetically related lineages, rendering evident that those mutations ar...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2711975/ https://www.ncbi.nlm.nih.gov/pubmed/19523237 http://dx.doi.org/10.1186/1471-2164-10-266 |