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Epistatic interactions modulate the evolution of mammalian mitochondrial respiratory complex components

BACKGROUND: The deleterious effect of a mutation can be reverted by a second-site interacting residue. This is an epistatic compensatory process explaining why mutations that are deleterious in some species are tolerated in phylogenetically related lineages, rendering evident that those mutations ar...

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Detalles Bibliográficos
Autores principales:	Azevedo, Luísa, Carneiro, João, van Asch, Barbara, Moleirinho, Ana, Pereira, Filipe, Amorim, António
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2711975/ https://www.ncbi.nlm.nih.gov/pubmed/19523237 http://dx.doi.org/10.1186/1471-2164-10-266

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