Structural Models of Human eEF1A1 and eEF1A2 Reveal Two Distinct Surface Clusters of Sequence Variation and Potential Differences in Phosphorylation

BACKGROUND: Despite sharing 92% sequence identity, paralogous human translation elongation factor 1 alpha-1 (eEF1A1) and elongation factor 1 alpha-2 (eEF1A2) have different but overlapping functional profiles. This may reflect the differential requirements of the cell-types in which they are express...

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Detalles Bibliográficos
Autores principales: Soares, Dinesh C., Barlow, Paul N., Newbery, Helen J., Porteous, David J., Abbott, Catherine M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2712093/
https://www.ncbi.nlm.nih.gov/pubmed/19636410
http://dx.doi.org/10.1371/journal.pone.0006315

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2712093/
https://www.ncbi.nlm.nih.gov/pubmed/19636410
http://dx.doi.org/10.1371/journal.pone.0006315

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