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Phosphodiesterase 1C is dispensable for rapid response termination of olfactory sensory neurons
In the nose, odorants are detected on the cilia of olfactory sensory neurons (OSNs), where a cAMP-mediated signaling pathway transforms odor stimulation into electrical responses. Phosphodiesterase (PDE) activity in OSN cilia was long thought to account for rapid response termination by degrading od...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2712288/ https://www.ncbi.nlm.nih.gov/pubmed/19305400 http://dx.doi.org/10.1038/nn.2289 |