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Hydrophobic profiles of the tail anchors in SLMAP dictate subcellular targeting

BACKGROUND: Tail anchored (TA) membrane proteins target subcellular structures via a C-terminal transmembrane domain and serve prominent roles in membrane fusion and vesicle transport. Sarcolemmal Membrane Associated Protein (SLMAP) possesses two alternatively spliced tail anchors (TA1 or TA2) but t...

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Detalles Bibliográficos
Autores principales: Byers, Joseph T, Guzzo, Rosa M, Salih, Maysoon, Tuana, Balwant S
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2712456/
https://www.ncbi.nlm.nih.gov/pubmed/19538755
http://dx.doi.org/10.1186/1471-2121-10-48