Hsp70 Chaperones and Type I PRMTs Are Sequestered at Intranuclear Inclusions Caused by Polyalanine Expansions in PABPN1

Genomic instability at loci with tandem arrays of simple repeats is the cause for many neurological, neurodegenerative and neuromuscular diseases. When located in coding regions, disease-associated expansions of trinucleotide repeats are translated into homopolymeric amino acid stretches of glutamin...

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Detalles Bibliográficos
Autores principales: Tavanez, João Paulo, Bengoechea, Rocio, Berciano, Maria T., Lafarga, Miguel, Carmo-Fonseca, Maria, Enguita, Francisco J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2712759/
https://www.ncbi.nlm.nih.gov/pubmed/19641605
http://dx.doi.org/10.1371/journal.pone.0006418

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2712759/
https://www.ncbi.nlm.nih.gov/pubmed/19641605
http://dx.doi.org/10.1371/journal.pone.0006418

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