Cargando…

The Depletion of Nuclear Glutathione Impairs Cell Proliferation in 3t3 Fibroblasts

BACKGROUND: Glutathione is considered essential for survival in mammalian cells and yeast but not in prokaryotic cells. The presence of a nuclear pool of glutathione has been demonstrated but its role in cellular proliferation and differentiation is still a matter of debate. PRINCIPAL FINDINGS: We h...

Descripción completa

Detalles Bibliográficos
Autores principales: Markovic, Jelena, Mora, Nancy J., Broseta, Ana M., Gimeno, Amparo, de-la-Concepción, Noelia, Viña, José, Pallardó, Federico V.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2712766/
https://www.ncbi.nlm.nih.gov/pubmed/19641610
http://dx.doi.org/10.1371/journal.pone.0006413