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The Depletion of Nuclear Glutathione Impairs Cell Proliferation in 3t3 Fibroblasts
BACKGROUND: Glutathione is considered essential for survival in mammalian cells and yeast but not in prokaryotic cells. The presence of a nuclear pool of glutathione has been demonstrated but its role in cellular proliferation and differentiation is still a matter of debate. PRINCIPAL FINDINGS: We h...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2712766/ https://www.ncbi.nlm.nih.gov/pubmed/19641610 http://dx.doi.org/10.1371/journal.pone.0006413 |