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Diabetes-Specific HLA-DR–Restricted Proinflammatory T-Cell Response to Wheat Polypeptides in Tissue Transglutaminase Antibody–Negative Patients With Type 1 Diabetes

OBJECTIVE: There is evidence of gut barrier and immune system dysfunction in some patients with type 1 diabetes, possibly linked with exposure to dietary wheat polypeptides (WP). However, questions arise regarding the frequency of abnormal immune responses to wheat and their nature, and it remains u...

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Detalles Bibliográficos
Autores principales: Mojibian, Majid, Chakir, Habiba, Lefebvre, David E., Crookshank, Jennifer A., Sonier, Brigitte, Keely, Erin, Scott, Fraser W.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2712773/
https://www.ncbi.nlm.nih.gov/pubmed/19401421
http://dx.doi.org/10.2337/db08-1579