In Vivo Activation of AMP-Activated Protein Kinase Attenuates Diabetes-Enhanced Degradation of GTP Cyclohydrolase I

OBJECTIVE: The activation of AMP-activated protein kinase (AMPK) has been reported to improve endothelial function. However, the targets of AMPK in endothelial cells remain poorly defined. The aim of this study was to test whether AMPK suppresses the degradation of GTP-cyclohydrolase (GTPCH I), a ke...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Shuangxi, Xu, Jian, Song, Ping, Viollet, Benoit, Zou, Ming-Hui
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2712774/
https://www.ncbi.nlm.nih.gov/pubmed/19528375
http://dx.doi.org/10.2337/db09-0267

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2712774/
https://www.ncbi.nlm.nih.gov/pubmed/19528375
http://dx.doi.org/10.2337/db09-0267

Ejemplares similares