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The Retinoblastoma Protein and Its Homolog p130 Regulate the G(1)/S Transition in Pancreatic β-Cells

OBJECTIVE: The retinoblastoma protein family (pRb, p130, p107) plays a central role in the regulation of cell cycle progression. Surprisingly, loss of pRb in the β-cell has no discernible effect on cell cycle control. Therefore, we explored the effects of individual loss of either p130 or p107 in ad...

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Detalles Bibliográficos
Autores principales: Harb, George, Vasavada, Rupangi C., Cobrinik, David, Stewart, Andrew F.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2712776/
https://www.ncbi.nlm.nih.gov/pubmed/19509021
http://dx.doi.org/10.2337/db08-0759