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The Retinoblastoma Protein and Its Homolog p130 Regulate the G(1)/S Transition in Pancreatic β-Cells
OBJECTIVE: The retinoblastoma protein family (pRb, p130, p107) plays a central role in the regulation of cell cycle progression. Surprisingly, loss of pRb in the β-cell has no discernible effect on cell cycle control. Therefore, we explored the effects of individual loss of either p130 or p107 in ad...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2712776/ https://www.ncbi.nlm.nih.gov/pubmed/19509021 http://dx.doi.org/10.2337/db08-0759 |