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Chronology of Islet Differentiation Revealed By Temporal Cell Labeling

OBJECTIVE: Neurogenin 3 plays a pivotal role in pancreatic endocrine differentiation. Whereas mouse models expressing reporters such as eGFP or LacZ under the control of the Neurog3 gene enable us to label cells in the pancreatic endocrine lineage, the long half-life of most reporter proteins makes...

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Detalles Bibliográficos
Autores principales: Miyatsuka, Takeshi, Li, Zhongmei, German, Michael S.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2712795/
https://www.ncbi.nlm.nih.gov/pubmed/19478145
http://dx.doi.org/10.2337/db09-0390