Glucagon-Like Peptide-1 Protects β-Cells Against Apoptosis by Increasing the Activity of an Igf-2/Igf-1 Receptor Autocrine Loop

OBJECTIVE: The gluco-incretin hormones glucagon-like peptide (GLP)-1 and gastric inhibitory peptide (GIP) protect β-cells against cytokine-induced apoptosis. Their action is initiated by binding to specific receptors that activate the cAMP signaling pathway, but the downstream events are not fully e...

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Detalles Bibliográficos
Autores principales: Cornu, Marion, Yang, Jiang-Yan, Jaccard, Evrim, Poussin, Carine, Widmann, Christian, Thorens, Bernard
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2712796/
https://www.ncbi.nlm.nih.gov/pubmed/19401425
http://dx.doi.org/10.2337/db09-0063

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2712796/
https://www.ncbi.nlm.nih.gov/pubmed/19401425
http://dx.doi.org/10.2337/db09-0063

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