Cargando…

Glucagon-Like Peptide-1 Protects β-Cells Against Apoptosis by Increasing the Activity of an Igf-2/Igf-1 Receptor Autocrine Loop

OBJECTIVE: The gluco-incretin hormones glucagon-like peptide (GLP)-1 and gastric inhibitory peptide (GIP) protect β-cells against cytokine-induced apoptosis. Their action is initiated by binding to specific receptors that activate the cAMP signaling pathway, but the downstream events are not fully e...

Descripción completa

Detalles Bibliográficos
Autores principales: Cornu, Marion, Yang, Jiang-Yan, Jaccard, Evrim, Poussin, Carine, Widmann, Christian, Thorens, Bernard
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2712796/
https://www.ncbi.nlm.nih.gov/pubmed/19401425
http://dx.doi.org/10.2337/db09-0063