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Mesenchymal Stem Cells Prevent the Rejection of Fully Allogenic Islet Grafts by the Immunosuppressive Activity of Matrix Metalloproteinase-2 and -9

OBJECTIVE: Mesenchymal stem cells (MSCs) are known to be capable of suppressing immune responses, but the molecular mechanisms involved and the therapeutic potential of MSCs remain to be clarified. RESEARCH DESIGN AND METHODS: We investigated the molecular mechanisms underlying the immunosuppressive...

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Detalles Bibliográficos
Autores principales: Ding, Yunchuan, Xu, Danmei, Feng, Gang, Bushell, Andrew, Muschel, Ruth J., Wood, Kathryn J.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2712800/
https://www.ncbi.nlm.nih.gov/pubmed/19509016
http://dx.doi.org/10.2337/db09-0317