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Desmoglein 1–dependent suppression of EGFR signaling promotes epidermal differentiation and morphogenesis

Dsg1 (desmoglein 1) is a member of the cadherin family of Ca(2+)-dependent cell adhesion molecules that is first expressed in the epidermis as keratinocytes transit out of the basal layer and becomes concentrated in the uppermost cell layers of this stratified epithelium. In this study, we show that...

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Detalles Bibliográficos
Autores principales: Getsios, Spiro, Simpson, Cory L., Kojima, Shin-ichiro, Harmon, Robert, Sheu, Linda J., Dusek, Rachel L., Cornwell, Mona, Green, Kathleen J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2712955/
https://www.ncbi.nlm.nih.gov/pubmed/19546243
http://dx.doi.org/10.1083/jcb.200809044