Ionic selectivity in L-type calcium channels by electrostatics and hard-core repulsion

A physical model of selective “ion binding” in the L-type calcium channel is constructed, and consequences of the model are compared with experimental data. This reduced model treats only ions and the carboxylate oxygens of the EEEE locus explicitly and restricts interactions to hard-core repulsion...

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Detalles Bibliográficos
Autores principales: Boda, Dezső, Valiskó, Mónika, Henderson, Douglas, Eisenberg, Bob, Gillespie, Dirk, Nonner, Wolfgang
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2712969/
https://www.ncbi.nlm.nih.gov/pubmed/19398776
http://dx.doi.org/10.1085/jgp.200910211

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2712969/
https://www.ncbi.nlm.nih.gov/pubmed/19398776
http://dx.doi.org/10.1085/jgp.200910211

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