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Intracellular calcium strongly potentiates agonist-activated TRPC5 channels
TRPC5 is a calcium (Ca(2+))-permeable nonselective cation channel expressed in several brain regions, including the hippocampus, cerebellum, and amygdala. Although TRPC5 is activated by receptors coupled to phospholipase C, the precise signaling pathway and modulatory signals remain poorly defined....
Autores principales: | Blair, Nathaniel T., Kaczmarek, J. Stefan, Clapham, David E. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2712973/ https://www.ncbi.nlm.nih.gov/pubmed/19398778 http://dx.doi.org/10.1085/jgp.200810153 |
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