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Quantitative proteomics identifies a Dab2/integrin module regulating cell migration

Clathrin-associated endocytic adapters recruit cargoes to coated pits as a first step in endocytosis. We developed an unbiased quantitative proteomics approach to identify and quantify glycoprotein cargoes for an endocytic adapter, Dab2. Surface levels of integrins β1, α1, α2, and α3 but not α5 or α...

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Detalles Bibliográficos
Autores principales: Teckchandani, Anjali, Toida, Natalie, Goodchild, Jake, Henderson, Christine, Watts, Julian, Wollscheid, Bernd, Cooper, Jonathan A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2712992/
https://www.ncbi.nlm.nih.gov/pubmed/19581412
http://dx.doi.org/10.1083/jcb.200812160