Mitochondrial Dysregulation of Osteoarthritic Human Articular Chondrocytes Analyzed by Proteomics: A Decrease in Mitochondrial Superoxide Dismutase Points to a Redox Imbalance

Mitochondria are involved in many cellular processes; mitochondrial dysfunctions have been associated with apoptosis, aging, and a number of pathological conditions, including osteoarthritis (OA). Mitochondrial proteins are attractive targets for the study of metabolism of the chondrocyte, the uniqu...

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Detalles Bibliográficos
Autores principales: Ruiz-Romero, Cristina, Calamia, Valentina, Mateos, Jesús, Carreira, Vanessa, Martínez-Gomariz, Montserrat, Fernández, Mercedes, Blanco, Francisco J.
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2713027/
https://www.ncbi.nlm.nih.gov/pubmed/18784066
http://dx.doi.org/10.1074/mcp.M800292-MCP200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2713027/
https://www.ncbi.nlm.nih.gov/pubmed/18784066
http://dx.doi.org/10.1074/mcp.M800292-MCP200

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