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Mitochondrial Dysregulation of Osteoarthritic Human Articular Chondrocytes Analyzed by Proteomics: A Decrease in Mitochondrial Superoxide Dismutase Points to a Redox Imbalance
Mitochondria are involved in many cellular processes; mitochondrial dysfunctions have been associated with apoptosis, aging, and a number of pathological conditions, including osteoarthritis (OA). Mitochondrial proteins are attractive targets for the study of metabolism of the chondrocyte, the uniqu...
Autores principales: | Ruiz-Romero, Cristina, Calamia, Valentina, Mateos, Jesús, Carreira, Vanessa, Martínez-Gomariz, Montserrat, Fernández, Mercedes, Blanco, Francisco J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2713027/ https://www.ncbi.nlm.nih.gov/pubmed/18784066 http://dx.doi.org/10.1074/mcp.M800292-MCP200 |
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