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Ag85B DNA vaccine suppresses airway inflammation in a murine model of asthma

BACKGROUND: In allergic asthma, Th2 lymphocytes are believed to play important roles in orchestrating airway eosinophilia and inflammation. Resetting the Th1/Th2 imbalance may have a therapeutic role in asthma. The mycobacterium tuberculosis 30-kilodalton major secretory protein (antigen 85B, Ag85B)...

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Detalles Bibliográficos
Autores principales: Wu, Jian, Xu, Jun, Cai, Chuang, Gao, Xinglin, Li, Li, Zhong, Nanshan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2713210/
https://www.ncbi.nlm.nih.gov/pubmed/19531238
http://dx.doi.org/10.1186/1465-9921-10-51