Modeling the role of p53 pulses in DNA damage- induced cell death decision

BACKGROUND: The tumor suppressor p53 plays pivotal roles in tumorigenesis suppression. Although oscillations of p53 have been extensively studied, the mechanism of p53 pulses and their physiological roles in DNA damage response remain unclear. RESULTS: To address these questions we presented an inte...

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Detalles Bibliográficos
Autores principales: Sun, Tingzhe, Chen, Chun, Wu, Yuanyuan, Zhang, Shuai, Cui, Jun, Shen, Pingping
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2713228/
https://www.ncbi.nlm.nih.gov/pubmed/19545411
http://dx.doi.org/10.1186/1471-2105-10-190

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2713228/
https://www.ncbi.nlm.nih.gov/pubmed/19545411
http://dx.doi.org/10.1186/1471-2105-10-190

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