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Modeling the role of p53 pulses in DNA damage- induced cell death decision
BACKGROUND: The tumor suppressor p53 plays pivotal roles in tumorigenesis suppression. Although oscillations of p53 have been extensively studied, the mechanism of p53 pulses and their physiological roles in DNA damage response remain unclear. RESULTS: To address these questions we presented an inte...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2713228/ https://www.ncbi.nlm.nih.gov/pubmed/19545411 http://dx.doi.org/10.1186/1471-2105-10-190 |