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Identification of osteopontin-dependent signaling pathways in a mouse model of human breast cancer
BACKGROUND: Osteopontin (OPN) is a secreted phosphoprotein which functions as a cell attachment protein and cytokine that signals through two cell adhesion molecules, α(v)β(3)-integrin and CD44, to regulate cancer growth and metastasis. However, the signaling pathways associated with OPN have not be...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2713255/ https://www.ncbi.nlm.nih.gov/pubmed/19570203 http://dx.doi.org/10.1186/1756-0500-2-119 |