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Preclinical Assessment of the Treatment of Second-Stage African Trypanosomiasis with Cordycepin and Deoxycoformycin

BACKGROUND: There is an urgent need to substitute the highly toxic compounds still in use for treatment of the encephalitic stage of human African trypanosomiasis (HAT). We here assessed the treatment with the doublet cordycepin and the deaminase inhibitor deoxycoformycin for this stage of infection...

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Detalles Bibliográficos
Autores principales: Vodnala, Suman K., Ferella, Marcela, Lundén-Miguel, Hilda, Betha, Evans, van Reet, Nick, Amin, Daniel Ndem, Öberg, Bo, Andersson, Björn, Kristensson, Krister, Wigzell, Hans, Rottenberg, Martin E.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2713411/
https://www.ncbi.nlm.nih.gov/pubmed/19652702
http://dx.doi.org/10.1371/journal.pntd.0000495