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Genomic deletion and promoter methylation status of Hypermethylated in Cancer 1 (HIC1) in mantle cell lymphoma

Mantle cell lymphomas (MCL), characterized by the t(11;14)(q13;q32), frequently carry secondary genetic alterations such as deletions in chromosome 17p involving the TP53 locus. Given that the association between TP53-deletions and concurrent mutations of the remaining allele is weak and based on ou...

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Detalles Bibliográficos
Autores principales: Stöcklein, Heike, Hutter, Grit, Kalla, Jörg, Hartmann, Elena, Zimmermann, Yvonne, Katzenberger, Tiemo, Adam, Patrick, Leich, Ellen, Höller, Sylvia, Müller-Hermelink, Hans Konrad, Rosenwald, Andreas, Ott, German, Dreyling, Martin
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2713485/
https://www.ncbi.nlm.nih.gov/pubmed/19669207
http://dx.doi.org/10.1007/s12308-008-0008-6