Severe Acute Respiratory Syndrome Coronavirus M Protein Inhibits Type I Interferon Production by Impeding the Formation of TRAF3·TANK·TBK1/IKKϵ Complex

Severe acute respiratory syndrome (SARS) coronavirus is highly pathogenic in humans and evades innate immunity at multiple levels. It has evolved various strategies to counteract the production and action of type I interferons, which mobilize the front-line defense against viral infection. In this s...

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Detalles Bibliográficos
Autores principales: Siu, Kam-Leung, Kok, Kin-Hang, Ng, Ming-Him James, Poon, Vincent K. M., Yuen, Kwok-Yung, Zheng, Bo-Jian, Jin, Dong-Yan
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2009
Materias:
Mechanisms of Signal Transduction
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2713514/
https://www.ncbi.nlm.nih.gov/pubmed/19380580
http://dx.doi.org/10.1074/jbc.M109.008227

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2713514/
https://www.ncbi.nlm.nih.gov/pubmed/19380580
http://dx.doi.org/10.1074/jbc.M109.008227

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