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Modulation of the immunogenicity of the Trypanosoma congolense cysteine protease, congopain, through complexation with α(2)-macroglobulin

The protozoan parasite Trypanosoma congolense is the main causative agent of livestock trypanosomosis. Congopain, the major lysosomal cysteine proteinase of T. congolense, contributes to disease pathogenesis, and antibody-mediated inhibition of this enzyme may contribute to mechanisms of trypanotole...

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Detalles Bibliográficos
Autores principales: Huson, Laura Elizabeth Joan, Authié, Edith, Boulangé, Alain François, Goldring, James Phillip Dean, Coetzer, Theresa Helen Taillefer
Formato: Texto
Lenguaje:English
Publicado: EDP Sciences 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2713678/
https://www.ncbi.nlm.nih.gov/pubmed/19549486
http://dx.doi.org/10.1051/vetres/2009036