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Modulation of the immunogenicity of the Trypanosoma congolense cysteine protease, congopain, through complexation with α(2)-macroglobulin
The protozoan parasite Trypanosoma congolense is the main causative agent of livestock trypanosomosis. Congopain, the major lysosomal cysteine proteinase of T. congolense, contributes to disease pathogenesis, and antibody-mediated inhibition of this enzyme may contribute to mechanisms of trypanotole...
Autores principales: | Huson, Laura Elizabeth Joan, Authié, Edith, Boulangé, Alain François, Goldring, James Phillip Dean, Coetzer, Theresa Helen Taillefer |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
EDP Sciences
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2713678/ https://www.ncbi.nlm.nih.gov/pubmed/19549486 http://dx.doi.org/10.1051/vetres/2009036 |
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