The biological basis for microRNA target restriction to the 3' untranslated region in mammalian mRNAs

MicroRNAs (miRNAs) interact with target sites located in 3' untranslated regions (3'UTR) of mRNAs to down-regulate their expression when the appropriate miRNA is bound to target mRNA. To establish the functional importance of target localization in the 3' UTR, we modified the stop cod...

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Detalles Bibliográficos
Autores principales: Gu, Shuo, Jin, Lan, Zhang, Feijie, Sarnow, Peter, Kay, Mark A.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2713750/
https://www.ncbi.nlm.nih.gov/pubmed/19182800
http://dx.doi.org/10.1038/nsmb.1552

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2713750/
https://www.ncbi.nlm.nih.gov/pubmed/19182800
http://dx.doi.org/10.1038/nsmb.1552

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