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The biological basis for microRNA target restriction to the 3' untranslated region in mammalian mRNAs
MicroRNAs (miRNAs) interact with target sites located in 3' untranslated regions (3'UTR) of mRNAs to down-regulate their expression when the appropriate miRNA is bound to target mRNA. To establish the functional importance of target localization in the 3' UTR, we modified the stop cod...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2713750/ https://www.ncbi.nlm.nih.gov/pubmed/19182800 http://dx.doi.org/10.1038/nsmb.1552 |