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Candida albicans cell surface superoxide dismutases degrade host-derived reactive oxygen species to escape innate immune surveillance

Mammalian innate immune cells produce reactive oxygen species (ROS) in the oxidative burst reaction to destroy invading microbial pathogens. Using quantitative real-time ROS assays, we show here that both yeast and filamentous forms of the opportunistic human fungal pathogen Candida albicans trigger...

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Detalles Bibliográficos
Autores principales: Frohner, Ingrid E, Bourgeois, Christelle, Yatsyk, Kristina, Majer, Olivia, Kuchler, Karl
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2713856/
https://www.ncbi.nlm.nih.gov/pubmed/19019164
http://dx.doi.org/10.1111/j.1365-2958.2008.06528.x