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Disorders of sex development expose transcriptional autonomy of genetic sex and androgen-programmed hormonal sex in human blood leukocytes

BACKGROUND: Gender appears to be determined by independent programs controlled by the sex-chromosomes and by androgen-dependent programming during embryonic development. To enable experimental dissection of these components in the human, we performed genome-wide profiling of the transcriptomes of pe...

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Detalles Bibliográficos
Autores principales: Holterhus, Paul-Martin, Bebermeier, Jan-Hendrik, Werner, Ralf, Demeter, Janos, Richter-Unruh, Annette, Cario, Gunnar, Appari, Mahesh, Siebert, Reiner, Riepe, Felix, Brooks, James D, Hiort, Olaf
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2713997/
https://www.ncbi.nlm.nih.gov/pubmed/19570224
http://dx.doi.org/10.1186/1471-2164-10-292