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Green tea polyphenol epigallocatechin-3-gallate inhibits advanced glycation end product-induced expression of tumor necrosis factor-α and matrix metalloproteinase-13 in human chondrocytes

INTRODUCTION: The major risk factor for osteoarthritis (OA) is aging, but the mechanisms underlying this risk are only partly understood. Age-related accumulation of advanced glycation end products (AGEs) can activate chondrocytes and induce the production of proinflammatory cytokines and matrix met...

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Detalles Bibliográficos
Autores principales: Rasheed, Zafar, Anbazhagan, Arivarasu N, Akhtar, Nahid, Ramamurthy, Sangeetha, Voss, Frank R, Haqqi, Tariq M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2714117/
https://www.ncbi.nlm.nih.gov/pubmed/19445683
http://dx.doi.org/10.1186/ar2700